Published September 28, 1983
by John Wiley & Sons Inc .
Written in English
|The Physical Object|
|Number of Pages||190|
Von Hippel-Lindau disease (VHL) is one of the most common inherited neoplasia syndromes and is characterized by highly vascular tumors of the eyes, brain, and spine, as well as benign and malignant tumors and/or cysts of the kidneys, adrenal medullae and sympathetic paraganglia, endolymphatic sac, epididymis, and broad ligament. Since the discovery of the VHL gene in , Cited by: Free Online Library: Neoplasia in Cri du Chat Syndrome from Italian and German Databases.(Case Report, Clinical report) by "Case Reports in Genetics"; Health, general Children Development and progression Diseases Cri du chat syndrome Care and treatment Case studies Diagnosis Cri-du-chat syndrome Pediatric diseases. J. GermanPatterns of neoplasia associated with the chromosome-breakage syndromes J. German (Ed.), Chromosome Mutation and Neoplasia, Cited by: 9. In: German J (ed) Chromosome mutation and neoplasia. Liss, New York, pp 97– Google Scholar German J, Archibald R, Bloom D () Chromosomal breakage in a rare and probably genetically determined syndrome of man.
In: German J (ed) Chromosome mutation and neoplasia. Liss, New York, pp 97 – Google Scholar German J, Archibald R, Bloom D () Chromosomal breakage in a rare and probably genetically determined syndrome of man. Children and adolescents who present with neuroendocrine tumors are at extremely high likelihood of having an underlying germline predisposition for the multiple endocrine neoplasia (MEN) syndromes, including MEN1, MEN2A and MEN2B, MEN4, and hyperparathyroid-jaw tumor . Cairns, J. Study of familial effects as a way of investigating the origin of human cancers. In "Chromosome mutation and neoplasia", ed. German, J., Liss. Inc, Cairns, J. & Logan J., Step by step into carcinogenesis. Nature , Cairns, J. Aging and the natural history of cancer. In "Prevention and treatment of cancer in the. "Doctor, there are some things man was never meant to tamper with" or positive, or neutral results of human working with genes, gene splicing, or accidental mutations, etcetera. Score A book’s total score is based on multiple factors, including the number of people who have voted for it and how highly those voters ranked the book.
Multiple endocrine neoplasia, type 1 (MEN1) is an inherited condition that causes tumors of the endocrine system (the body's network of hormone-producing glands).People affected by MEN1 typically develop tumors of the parathyroid gland, the pituitary gland, and the pancreas, although other glands may be involved as tumors are often "functional" and secrete excess hormones, . Cri du Chat syndrome (CdC) is a chromosomal abnormality (deletion of short arm of chromosome 5) associated with intellectual disability and typical anatomical abnormalities. Research up to now focuses on the management of the disease during childhood. The longer lifespan of these patients warrants deeper investigations of how and if aging could be affected by the syndrome. Schaaf, L, et al. Developing effective screening strategies in multiple endocrine neoplasia type 1 (MEN 1) on the basis of clinical and sequencing data of German patients with MEN 1. Exp. Clin. Endocrinol. Diabetes. ; (8) PMID: ; Giusti, F, et al. Multiple Endocrine Neoplasia Type 1. Aug In: Pagon, RA, et al. Germline mutations in the VHL protein (pVHL) is at the root of VHL The gene is located on the short arm of chromosome 3p. 37 VHL is caused by an inactivation of pVHL and subsequent overproduction of vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and transforming growth factor (TGF)-α. 37 In vivo, pVHL acts as a tumor suppressor by binding to a .